Personal Statement
I am Professor of Protein Bioinformatics in the Institute of Systems, Molecular and Integrative Biology. My interests span the broad relationships between protein sequences, structures and functions and how these evolve with time. As such, I apply a wide range of bioinformatics tools - but especially modelling software like AlphaFold - to diverse proteins of interest. This leads to interesting collaborations across the Institute and more broadly. I apply structural bioinformatics developments to produce software for experimental structural biology, with recent work exploring structure validation. Most recently, we have become interested in applying protein structure predictions to gene annotation, both structural and function.

Positions are available for PhD study in protein structure-function-evolution and crystallographic or cryo-EM methods. If you are in receipt of sponsorship, please contact me to discuss opportunities and projects.