Dr
Stephen AstonProfile page
Senior Clinical Lecturer in Infectious Diseases
Pharmacology & Therapeutics
- Senior Clinical Lecturer in Infectious DiseasesPharmacology & Therapeutics
ABOUT
Personal Statement
Following PhD work based in Malawi on diagnosis and management of community-acquired pneumonia in adults living with HIV in low-resource settings, I returned to Liverpool to complete my clinical training in infectious diseases and general internal medicine. Having returned to a clinical academic role, within CAMO-Net and related ventures in Liverpool, I undertake a portfolio of multidisciplinary and clinically-oriented research exploring strategies to mitigate the progression of antimicrobial resistance through optimised antibiotic prescribing in a variety of contexts - particularly in the management of suspected sepsis/serious bacterial infection and respiratory infection.
Research Overview
I undertake a portfolio of multidisciplinary and clinically-oriented research exploring strategies to mitigate the progression of antimicrobial resistance through optimised antibiotic prescribing in a variety of contexts - particularly in the management of suspected sepsis/serious bacterial infection and acute and chronic respiratory infection. My current projects relate to three broad avenues of work: (1) Examining the use of artificial-intelligence and machine-learning enabled analysis of routinely collected electronic health record data to support data-driven diagnosis of infection at both individual patient and health system levels; (2) Pragmatic clinical trials of interventions to minimise unnecessary antibiotic prescribing in suspected sepsis/serious bacterial infection; (3) Optimising selection, delivery and monitoring of complex antibiotic regimens in chronic respiratory infections, in particular non-tuberculous mycobacteria.
UNIVERSITY OF LIVERPOOL ORGANISATIONAL UNITS MEMBERSHIP
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